The 5-endo-trigCyclization of gem-Difluoroolefins with sp3Carbon Nucleophiles: Synthesis of 1-Fluorocyclopentenes
| Autor: | Ichikawa, Junji, Sakoda, Kotaro, Wada, Yukinori |
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| Zdroj: | Chemistry Letters; March 2002, Vol. 31 Issue: 3 p282-283, 2p |
| Abstrakt: | A disfavored 5-endo-trigcyclization is accomplished in gem-difluoroolefins with sp3carbon nucleophiles, generated viathe lithium–iodine exchange reaction of 1,1-difluoro-5-iodo-1-pentenes with tert-butyllithium, to afford 1-fluorocyclopentenes. |
| Databáze: | Supplemental Index |
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