| Autor: |
Ohki, Minoru, Takenaka, Akio, Shimanouchi, Hirotaka, Sasada, Yoshio |
| Zdroj: |
Bulletin of the Chemical Society of Japan; December 1976, Vol. 49 Issue: 12 p3493-3497, 5p |
| Abstrakt: |
The complex crystals of 5-bromocytosine and N-tosyl-l-glutamic acid were obtained from their aqueous solution. The space group is P1 with dimensions of a=10.843(1), b=11.690(2), c=10.879(2) Å, a=122.15(1), ß=121.38(1), ?=69.93(1)°, and Z=2. The structure was solved by the heavy atom method and refined by a block-diagonal least-squares method. The undissociated ?-carboxyl group of glutamic acid is bound with O(2) and N(4) of 5-bromocytosine through hydrogen bonds. This interaction mode is different from those found in some cytosine : glycine complexes and cytidine : N-benzyloxycarbonyl-l-glutamic acid complex dihydrate in which the dissociated a-carboxyl group plays a role. This is the first example of interaction between cytosine and the acidic side group of amino acid. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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