Autor: |
Ueki, Masaaki, Goto, Mitsutaka, Okumura, Jin, Ishii, Yusuke |
Zdroj: |
Bulletin of the Chemical Society of Japan; August 1998, Vol. 71 Issue: 8 p1887-1898, 12p |
Abstrakt: |
Synthesis and evaluation of three Fmoc–phosphotyrosine derivatives with a phosphate group protected as N,N'-dialkyldiamide (alkyl = Prn, Pri, and Bui) were studied. All the derivatives were obtained as crystals, among which the Buiderivative (4c) was the best in ease of preparation and excellence in cleavage property. Solid phase synthesis of a methionine-containing peptide, H–Tyr(PO3H2)–Val–Pro–Met–Leu–OH, could be done without any problems. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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