| Autor: |
Gomktsyan, Tiruhi, Khachatryan, Angelina, Avakyan, Diana, Hunanyan, Lernik, Shainova, Roza, Karapetyan, Armen, Ghazaryan, Emma, Vorskanyan, Asya, Dovlatyan, Margarita, Gharibyan, Yana, Yengoyan, Aleksandr, Pivazyan, Vergush |
| Zdroj: |
Green Processing & Synthesis; November 2023, Vol. 12 Issue: 1 |
| Abstrakt: |
Eco-friendly ultrasound-assisted synthesis of a series of 3-N-substituted 6-((4-(butylamino)-6-(diethylamino)-1,3,5-triazin-2-yl)oxy)pyridazin-3(2H)-one derivatives and in silicostudy to predict their biological activities were carried out. Physicochemical and pharmacokinetic properties were obtained. Absorption, distribution, metabolism, excretion and toxicity properties and bioavailability index were calculated. A comparative analysis of structural similarity based on the Tanimoto coefficient was carried out. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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