Autor: |
Barajas, Juan M., Rasouli, Milad, Umeda, Masayuki, Hiltenbrand, Ryan, Abdelhamed, Sherif, Mohnani, Rebecca, Arthur, Bright, Westover, Tamara, Thomas, Melvin E., Ashtiani, Minoo, Janke, Laura J., Xu, Beisi, Chang, Ti-Cheng, Rosikiewicz, Wojciech, Xiong, Emily, Rolle, Chandra, Low, Jonathan, Krishan, Reethu, Song, Guangchun, Walsh, Michael P., Ma, Jing, Rubnitz, Jeffrey E., Iacobucci, Ilaria, Chen, Taosheng, Krippner-Heidenreich, Anja, Zwaan, Christian M., Heidenreich, Olaf, Klco, Jeffery M. |
Zdroj: |
Blood; February 2024, Vol. 143 Issue: 7 p619-630, 12p |
Abstrakt: |
•UBTF tandem duplications and KMT2A/menin complex co-occupy genomic targets dysregulated in UBTF-TD acute myeloid leukemias.•UBTF-TD acute myeloid leukemias are sensitive to menin inhibition. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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