Sc(OTf)3-Catalyzed Domino C–C/C–N Bond Formation of Aziridines with Quinones via Radical Pathway

Autor: Verma, Kshitiz, Mishra, Manmath, Maharana, Prabhat Kumar, Bhattacharyya, Hemanga, Saha, Sharajit, Punniyamurthy, Tharmalingam
Zdroj: Organic Letters; November 2023, Vol. 25 Issue: 43 p7933-7938, 6p
Abstrakt: Sc(III)-catalyzed domino C–C and C–N bond formation of N-sulfonyl aziridines with quinones has been accomplished to furnish functionalized indolines at a moderate temperature. The umpolung reactivity of aziridines, radical pathway, mild reaction conditions, substrate scope, and coupling of drug molecules in a postsynthetic application are the important practical features.
Databáze: Supplemental Index