Could 68Ga-DOTA-UBI-29-41 Help Identify Chronic Osteomyelitis on PET/CT Images? A Pilot Study

Autor: Nogueira, Solange Amorim, de Barboza, Marycel F., Dell’Aquila, Adriana M., Santos, Durval C. B, Osawa, Akemi
Zdroj: Clinical Nuclear Medicine; November 2023, Vol. 48 Issue: 11 p982-984, 3p
Abstrakt: This pilot study aimed to confirm the presence of infectious agents in infection foci using PET/CT imaging with 68Ga-DOTA-UBI(29–41)in 7 patients with chronic osteomyelitis and with indications for surgical cleaning at the site of the infection focus. The whole-body PET/CT was performed on Biograph mCT 40 PET/CT scanner (Siemens Healthineers); the image began 45–60 minutes postinjection of the radiotracer (148–260 MBq). This study demonstrated that, in 6 patients in whom the PET/CT was classified as positive for identified infectious foci, confirmed by culture of the secretion sample collected during surgery, only 1 patient in antibiotic therapy was negative.
Databáze: Supplemental Index