| Autor: |
Wang, Sen, Bai, Luge, Hu, Xiaoxuan, Yao, Siqi, Hao, Zhiyan, Zhou, JiaJia, Li, Xiao, Lu, Haixia, He, Jiankang, Wang, Ling, Li, Dichen |
| Zdroj: |
Advanced Healthcare Materials; October 2023, Vol. 12 Issue: 25 |
| Abstrakt: |
3D Bioprinting In vitro neurovascular unit (NVU) models are valuable for investigating brain functions and developing drugs. However, it remains challenging to recapitulate the native architectural features and ultra‐soft extracellular matrix (ECM) properties. In article 2300004, Ling Wang, Dichen Li, and co‐workers propose a novel two‐stage bioprinting methodology with collagen‐based low‐viscosity composites, for functional 3D neurovascular constructs modeling in vitro with low modulus of ECM and high fidelity. The model shows selective barrier properties and distinct expression of critical proteins. |
| Databáze: |
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