TCRαβ/CD19 cell-depleted HLA-haploidentical transplantation to treat pediatric acute leukemia: updated final analysis.

Autor: Merli, Pietro, Algeri, Mattia, Galaverna, Federica, Bertaina, Valentina, Lucarelli, Barbarella, Boccieri, Emilia, Becilli, Marco, Quagliarella, Francesco, Rosignoli, Chiara, Biagini, Simone, Girolami, Elia, Meschini, Antonella, Del Principe, Giovanna, Sborgia, Raffaella, Catanoso, Maria Luigia, Carta, Roberto, Strocchio, Luisa, Pinto, Rita Maria, Buldini, Barbara, Falco, Michela, Meazza, Raffaella, Pende, Daniela, Andreani, Marco, Pira, Giuseppina Li, Pagliara, Daria, Locatelli, Franco
Zdroj: Blood; 20230101, Issue: Preprints
Abstrakt: -TCRαβ/CD19-cell depleted haploHSCT is characterized by low TRM and acute/chronic GVHD, with OS and DFS similar to other transplants-Use of TBI in the conditioning regimen, transplant in CR1/2 and low/negative levels of MRD are associated with improved outcome
Databáze: Supplemental Index