Transferrin-mediated uptake of aluminium by human parathyroid cells results in reduced parathyroid hormone secretion.

Autor: Smans, K A, D'Haese, P C, Van Landeghem, G F, Andries, L J, Lamberts, L V, Hendy, G N, De Broe, M E
Zdroj: Nephrology Dialysis Transplantation; September 2000, Vol. 15 Issue: 9 p1328-1336, 9p
Abstrakt: The present study investigates whether aluminium-transferrin (Al-Tf) uptake by Tf receptor-mediated endocytosis induces hypoparathyroidism and thus might contribute to the increasing prevalence of adynamic bone disease (ABD) in the current dialysis population.
Databáze: Supplemental Index