| Autor: |
Larizza, Maria A, Dooley, Michael J, Stewart, Kay, Kong, David CM |
| Zdroj: |
Journal of Pharmacy Practice and Research; June 2006, Vol. 36 Issue: 2 p115-118, 4p |
| Abstrakt: |
To identify factors influencing adherence to oral molecular therapies in haematology‐oncology outpatients. Patients prescribed imatinib and thalidomide participated in the study. A quantitative questionnaire incorporating validated assessment tools and developed from issues raised in the literature was used to collect data about demographic characteristics, motivations and perceptions, impact of social environment, and aspects of medication regimens. These factors were assessed for association with adherence to molecular therapies, estimated using the Morisky score. 24 patients were recruited, all of whom reported high or moderate adherence to oral molecular therapies based on their Morisky score. Adherence was positively related with age (Rho = +0.510; p = 0.011) and overall patient satisfaction with hospital services and support from family and friends (Rho = +0.609; p = 0.003). There were a number of social environment factors which were found to have a significant inverse relationship with adherence to molecular therapies including: forgetting to take the medication, change in daily routine, feeling sick/ill, wanting to avoid adverse effects and having problems taking medication at certain times. The overall impact of a patient's social environment was found to contribute negatively to adherence (Rho = −0.542; p = 0.017). Factors affecting adherence to molecular therapies can be assessed by pharmacists, allowing implementation of strategies to encourage adherent behaviour in difficult circumstances. |
| Databáze: |
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