Inhalable Chitosan-Based Hydrogel as a Mucosal Adjuvant for Hydroxychloroquine in the Treatment for SARS-CoV-2 Infection in a Hamster Model

Autor: Shu-Han Lin, Donna, Tzeng, Shian Chiuan, Cha, Tai-Lung, Hung, Chin-Mao, Lin, Wen-Chin, Yang, Chuen-Mi, Lu, Hsuan-Ying, Chang, Jia-Yu, Huang, Shu-Wei
Zdroj: Journal of Microbiology, Immunology and Infection; 20230101, Issue: Preprints
Abstrakt: Effective therapy for COVID-19 remains limited. Hydroxychloroquine (HCQ) has been considered, but safety and efficacy concerns remain. Chitosan exhibits antiviral and immunomodulatory effects, yet how the combination of HCQ and chitosan performs in treating COVID-19 is unknown.
Databáze: Supplemental Index