| Autor: |
Toren, E.Clifford, Vacik, Dorothy N., Mockridge, Peter B. |
| Zdroj: |
Journal of Chromatography A; August 1983, Vol. 266 Issue: 1 p207-212, 6p |
| Abstrakt: |
We describe a rapid, simple, and sensitive high-performance liquid chromatographic method for the determination of hemoglobin A1c. with a bonded-phase cation-exchange column. About five measurements are obtained per hour on small quantities of whole blood. Sample preparation requires no centrifugation or washing of cells. The results correlate well (r= 0.918, n= 51) with a commercially available, disposable mini-column kit. The results are insensitive to small changes in pH and temperature. Variants arising from hemoglobinopathies display different chromatographic profiles. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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