Accuracy of spleen stiffness measurement for the diagnosis of clinically significant portal hypertension in patients with compensated advanced chronic liver disease: a systematic review and individual patient data meta-analysis

Autor: Dajti, Elton, Ravaioli, Federico, Zykus, Romanas, Rautou, Pierre-Emmanuel, Elkrief, Laure, Grgurevic, Ivica, Stefanescu, Horia, Hirooka, Masashi, Fraquelli, Mirella, Rosselli, Matteo, Chang, Pik Eu Jason, Piscaglia, Fabio, Reiberger, Thomas, Llop, Elba, Mueller, Sebastian, Marasco, Giovanni, Berzigotti, Annalisa, Colli, Agostino, Festi, Davide, Colecchia, Antonio, Alemanni, Luigina Vanessa, Vestito, Amanda, Renzulli, Matteo, Azzaroli, Francesco, Colecchia, Luigi, Castera, Laurent, Ronot, Maxime, Platon-Lupsor, Monica, Nicoara-Farcau, Oana, Ignat, Mina, Hias, Yoichi, Fichera, Anna, Ooi, Chin Chin, Borghi, Alberto, Bauer, David, Semmler, Georg, Mandorfer, Mattias, Calleja, José Luis, Elshaarawy, Omar, Romagnoli, Dante
Zdroj: The Lancet Gastroenterology & Hepatology; September 2023, Vol. 8 Issue: 9 p816-828, 13p
Abstrakt: The diagnosis of clinically significant portal hypertension is crucial for prognosis and treatment guidance in patients with compensated advanced chronic liver disease (ACLD). Spleen stiffness measurement (SSM) might improve the non-invasive diagnosis of clinically significant portal hypertension, but previous studies have reported heterogeneous SSM cutoffs. We aimed to evaluate the accuracy of SSM and SSM-based algorithms in this setting.
Databáze: Supplemental Index