Association of E23K (rs5219) polymorphism in the KCNJ11gene with type 2 diabetes mellitus risk in Jordanian population

Autor: Al-Khalayfa, Sawsan, Mashal, Safaa, Khanfar, Mariam, Srour, Luma, Mustafa, Lina, Battah, Abdelkader, Zayed, Ayman A., Khader, Yousef S., Azab, Bilal
Zdroj: Human Gene; 20230101, Issue: Preprints
Abstrakt: The E23K (rs5219) polymorphism in the potassium channel inward-rectifying subfamily J member 11(KCNJ11) gene has been implicated with type 2 diabetes mellitus (T2DM) in several previous studies. However, contradictory findings observing a lack of association between this polymorphism and T2DM were also documented. For that reason, we investigated the E23K (rs5219) polymorphism relation to T2DM among Jordanians, analyzed its genotypic and allelic frequencies, and compared them with the findings among other populations.
Databáze: Supplemental Index