Expedient Synthesis of Triazole-Linked Glycosyl Amino Acids and Peptides

Autor: Kuijpers, B. H. M., Groothuys, S., Keereweer, A. R., Quaedflieg, P. J. L. M., Blaauw, R. H., Delft, F. L. van, Rutjes, F. P. J. T.
Zdroj: Organic Letters; September 2004, Vol. 6 Issue: 18 p3123-3126, 4p
Abstrakt: An expedient, high-yielding synthesis of two types of triazole-linked glycopeptides is described. These novel and stable glycopeptide mimics were prepared via Cu(I)-catalyzed [3 + 2] cycloaddition of either azide-functionalized glycosides and acetylenic amino acids or acetylenic glycosides and azide-containing amino acids.
Databáze: Supplemental Index