| Autor: |
Zeng, Baoxing, Li, Yanzhou, Liu, Guoping, Cui, Qingqing, Tang, Feng, Shi, Dongying, Chen, Lijuan, Zhao, Junwei |
| Zdroj: |
Inorganic Chemistry; July 2023, Vol. 62 Issue: 26 p10351-10358, 8p |
| Abstrakt: |
An attractive isonicotinic acid-ornamented octa-CeIII-inserted phospho(III)tungstate [H2N(CH3)2]6Na8[Ce8(H2O)30W8Na2O20(INA)4][HPIIIW4O17]2[HPIIIW9O33]4·30H2O (1-Ce) (HINA = isonicotinic acid) has been isolated through the deliberately designed one-step assembly strategy, in which the HPO32–heteroanion template was introduced into the Ce3+/WO42–system in the presence of HINA. The polyoxoanion of 1-Ceconsists of two identical [Ce4(H2O)15W4NaO10(INA)2][HPIIIW4O17][HPIIIW9O33]2}7–subunits linked by Ce–O–W bonds. The polyoxoanion exhibits three kinds of polyoxotungstate building blocks [W4NaO20(INA)2]17–, [HPIIIW4O17]6–, and [HPIIIW9O33]8–, in which [W4NaO20(INA)2]17–and [HPIIIW4O17]6–building units can be considered as seeds driven by the coordination of additional Ce3+ions to induce aggregation of [HPIIIW9O33]8–fragments. Furthermore, 1-Cepossesses high peroxidase-like activity and can oxidize 3,3′,5,5′-tetramethylbenzidine in the presence of H2O2with a turnover rate of 6.20 × 10–3s–1. Because l-cysteine (l-Cys) can reduce oxTMB to TMB, the detection of l-Cys was established based on the 1-Ce-based H2O2colorimetric biosensing platform with the linear range of 5–100 μM and the limit of detection of 4.28 μM. This work not only can expand the scientific research studies on coordination chemistry and materials chemistry of rare-earth-inserted polyoxotungstates but also can provide practical application possibility in clinical diagnosis using liquid biopsy. |
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