Neurobehavioral precursors of compulsive cocaine-seeking in dual fronto-striatal circuits

Autor: Jones, Jolyon A., Belin-Rauscent, Aude, Jupp, Bianca, Fouyssac, Maxime, Sawiak, Stephen J., Zuhlsdorff, Katharina, Zhukovsky, Peter, Hebdon, Lara, Sanchez, Clara Velazquez, Robbins, Trevor W., Everitt, Barry J., Belin, David, Dalley, Jeffrey W.
Zdroj: Biological Psychiatry Global Open Science; 20230101, Issue: Preprints
Abstrakt: Only some individuals using drugs recreationally eventually develop a substance use disorder, characterised in part by the rigid engagement in drug foraging behaviour (drug seeking), often maintained in the face of adverse consequences (e.g., is compulsive). The neurobehavioral determinants of this individual vulnerability have not been fully elucidated.
Databáze: Supplemental Index