| Autor: |
Tesi, Godswill Okeoghene, Kpomah, Enyohwo D., Ossai, Jude Chinedu, Apiamu, Augustine, Orji, Orji J., Olorunfemi, Daniel I. |
| Zdroj: |
Chemistry Africa; December 2023, Vol. 6 Issue: 6 p3145-3152, 8p |
| Abstrakt: |
The presence of hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) in urine has been used to assess the exposure, metabolic activation, and risks of these carcinogens. Thus, this study is aimed at investigating the concentration and risk of OH-PAHs among commercial motorcyclists in southern, Nigeria. Urine samples were collected early in the morning from forty volunteer commercial cyclists who participated in this study. The OH-PAHs were quantified in the urines using high performance liquid chromatography (HPLC) after hydrolysis. Result showed that ∑8 OH-PAHs varied significantly, ranging from 0.04 to 24.48 ng mL− 1for all the urine samples collected. The occurrence pattern follows the order: 3-OHFlu > 1-OHPhen > 2-OHNap > 2-OHFlu > 1-OHNap > 3-OHPhen > 4-OHPhen > 1-OHPyr. There was no significant variation of OH-PAHs with personal factors such as smoking, age and years of working. However, the hazard index (HI) values for the OH-PAHs were above 1 and indicated that there is adverse non-carcinogenic risk for the commercial motorcyclists. The use of personal protective equipment is therefore encouraged among commercial motorcyclists. |
| Databáze: |
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