| Autor: |
Lichtenthäler, Luisa C., Pussin, Andreas M., Aach, Mirko, Grasmücke, Dennis, Schildhauer, Thomas A., Schmiegel, Wolff, Brechmann, Thorsten |
| Zdroj: |
Spinal Cord; 20230101, Issue: Preprints p1-7, 7p |
| Abstrakt: |
Study design: Retrospective matched case-control study including patients with spinal cord injury who presented with an anus-near pressure injury. Two groups were formed based on the presence of a diverting stoma. Objectives: To evaluate the primary microbial colonisation and secondary infection of anus-near pressure injuries depending on the presence of a pre-existing diverting stoma and to investigate the effect on the wound healing. Setting: University hospital with a spinal cord injury unit. Methods: A total of 120 patients who had undergone surgery of an anus-near decubitus stage 3 or 4 were included in a matched-pair cohort study. Matching was realised according to age, gender, body mass index and general condition. Results: The most common species in both groups was Staphylococcus spp.(45.0%). The only significantly different primary colonisation affected Escherichia coli, that was found in the stoma patients less often (18.3 and 43.3%, p< 0.01). A secondary microbial colonisation occurred in 15.8% and was equally distributed, except for Enterococcus spp. that was present in the stoma group only (6.7%, p< 0.05). The time to complete cure took longer in the stoma group (78.5 versus 57.0 days, p< 0.05) and was associated with a larger ulcer size (25 versus 16 cm2, p< 0.01). After correction for the ulcers’ size, there was no association to outcome parameters such as overall success, healing time or adverse events. Conclusions: The presence of a diverting stoma alters the microbial flora of an anus-near decubitus slightly without impact on the healing process. |
| Databáze: |
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