| Autor: |
Tan, Zhengguo, Unterberg-Buchwald, Christina, Blumenthal, Moritz, Scholand, Nick, Schaten, Philip, Holme, Christian, Wang, Xiaoqing, Raddatz, Dirk, Uecker, Martin |
| Zdroj: |
IEEE Transactions on Medical Imaging; 2023, Vol. 42 Issue: 5 p1374-1387, 14p |
| Abstrakt: |
This work introduced a stack-of-radial multi-echo asymmetric-echo MRI sequence for free-breathing liver volumetric acquisition. Regularized model-based reconstruction was implemented in Berkeley Advanced Reconstruction Toolbox (BART) to jointly estimate all physical parameter maps (water, fat, ${R}_{{2}}^{\ast}$ , and ${B}_{{0}}$ field inhomogeneity maps) and coil sensitivity maps from self-gated ${k}$ -space data. Specifically, locally low rank and temporal total variation regularization were employed directly on physical parameter maps. The proposed free-breathing radial technique was tested on a water/fat & iron phantom, a young volunteer, and obesity/diabetes/hepatic steatosis patients. Quantitative fat fraction and $R_{2}^{\ast}$ accuracy were confirmed by comparing our technique with the reference breath-hold Cartesian scan. The multi-echo radial sampling sequence achieves fast ${k}$ -space coverage and is robust to motion. Moreover, the proposed motion-resolved model-based reconstruction allows for free-breathing liver fat and ${R}_{{2}}^{\ast}$ quantification in multiple motion states. Overall, our proposed technique offers a convenient tool for non-invasive liver assessment with no breath holding requirement. |
| Databáze: |
Supplemental Index |
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