Chemical Composition of Goniothalamus andersoniiBark and its Mosquito Repellent Activity

Autor: Muhamad Dah, Norsyazwani, Wan Ahmad, Wan Yaacob, Mat Noor, Mohd Syafiq Aiman, Abdul Azziz, Saripah Salbiah Syed
Zdroj: Analytical Chemistry Letters; January 2023, Vol. 13 Issue: 1 p17-27, 11p
Abstrakt: AbstractThis study sought to identify the chemical composition of smoke condensate of Goniothalamus andersonii(Annonaceae) and comparatively evaluate the effectiveness of smoke condensate. The chemical composition has been determined by GC-MS. Five main components were contained in aqueous fraction, namely eugenol (25.31%), (E)-cinnamaldehyde (21.13%), hexamethylene diacrylate (7.0%), caryophyllene (6.25%), and ethyl oleate (4.3%). While, three main components were detected in the n-hexane fractions, namely guaiol (8.98%), α-eudesmol (5.71%), and (-)-cyperene (3.06%). Laboratory research was conducted to determine the repellency of the smoke condensate of Aedes aegyptimosquitoes at two levels of concentration (5.0% and 10.0%). Tests were carried out to establish the percentage reduction of mosquito landing for each of the concentrations. The synthetic insect repellent, N, N-diethyl-m-toluamide (DEET), was used as a standard at a similar level of concentration. At 5.0% concentration, DEET provided a better percentage reduction with 70.5% for up to 4 hours, compared to smoke condensate (44.5%). At 10.0%, DEET provided an 80.9% reduction in mosquito landing, which was significantly better, as compared to smoke condensate (61.9%). However, data analysis through a t-test demonstrated a significant difference between smoke condensate and DEET efficacy in both concentrations, with regards to treated and untreated arms (P< 0.05).
Databáze: Supplemental Index