| Abstrakt: |
Research has shown mixed results when comparing in‐hospital complications following atrial fibrillation ablation in women compared to men. To better quantify sex differences and in‐hospital outcomes in atrial fibrillation ablation procedures and identify factors associated with poorer outcomes. We queried the NIS database from 2016 to 2019 for hospitalizations with a primary diagnosis of atrial fibrillation ablation and excluded patients with any other arrhythmias, ICD/pacemaker placement. We assessed demographics, in‐hospital mortality, and complications of women compared to men. Admissions for atrial fibrillation were more common in females than males (849 050 vs. 815 665; p< .001). However, females were less likely to receive ablation (1.65% vs. 2.71%, OR: 0.60; 95% confidence interval: 0.57–0.64, p< .001), which persisted after adjusting for cardiomyopathy (adjusted OR: 0.61; 95% confidence interval: 0.58–0.65, p< .001). The primary outcome of in‐hospital mortality was not statistically different in univariate analysis (0.39% vs. 0.36%, OR: 1.09, 95% CI: 0.44–2.72, p= .84), finding that did not change when adjusted for comorbidities (adjusted OR: 0.94, 95% CI: 0.36–2.49). The complication rate in hospitalized patients following ablation was 8.08%. The total unadjusted complication rate was higher for females than males (9.58% vs. 7.09%, p= .001); however, it was not significant when adjusted for risks (adjusted OR: 1.23, 95% CI: 0.99–1.53, p= .06). Female sex is not associated with increased complications or death in a real‐world study of catheter ablation when results are adjusted for risks. However, females admitted with atrial fibrillation receive ablation less often than males during hospital admission. Women make up a larger group of admitted atrial fibrillation patients than males. However, women with atrial fibrillation had a 39% lower likelihood of receiving catheter ablation in the hospital when compared to men. In‐hospital mortality was not statistically different between women and men in univariate and multivariate analyses. The total unadjusted complication rate was higher for women than men; however, it was insignificant when adjusted for risks. When controlled for risk factors, female sex was not associated with increased complications or in‐hospital death in a real‐world study. |
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