In vivogeneration of thrombin in patients with liver disease without apparent evidence of activation of the intrinsic or extrinsic pathway of coagulation

Autor: Elvers, Fynn L., Stamouli, Marilena, Adelmeijer, Jelle, Jeyanesan, Dhaarica, Bernal, William, Maas, Coen, Patel, Vishal C., Lisman, Ton
Zdroj: Journal of Thrombosis and Haemostasis; August 2023, Vol. 21 Issue: 8 p2078-2088, 11p
Abstrakt: Patients with liver diseases are in a hypercoagulable state, as evidenced by enhanced in vitrothrombin generating capacity and elevated plasma levels of markers of in vivothrombin generation. However, it is unknown by which mechanism in vivoactivation of coagulation occurs.
Databáze: Supplemental Index