Single priming and booster dose of ten-valent and 13-valent pneumococcal conjugate vaccines and Streptococcus pneumoniaecolonisation in children in South Africa: a single-centre, open-label, randomised trial

Autor: Olwagen, Courtney P, Izu, Alane, Mutsaerts, Eleonora A M L, Jose, Lisa, Koen, Anthonet, Downs, Sarah L, Van Der Merwe, Lara, Laubscher, Matt, Nana, Amit J, Moultrie, Andrew, Cutland, Clare L, Dorfman, Jeffrey R, Madhi, Shabir A
Zdroj: The Lancet Child & Adolescent Health; 20230101, Issue: Preprints
Abstrakt: Pneumococcal conjugate vaccine (PCV) immunisation has reduced vaccine-serotype colonisation and invasive pneumococcal disease in South Africa, providing the opportunity to consider transitioning from a two-dose (2 + 1) to one-dose (1 + 1) primary series and a booster dose.
Databáze: Supplemental Index