| Abstrakt: |
The clinical finding that acute hyperventilation by intermittent positive pressure may produce a progressive reduction in Pa02has stimulated a theoretical analysis of the factors involved. When Pa02is below approximately 75 mm. Hg at Paco240 mm. Hg, hyperventilation will produce a reduction in Pa02. This will be offset if, coincidently, physiological shunt is reduced or cardiac output is increased. The effect will be exaggerated if cardiac output is impaired or physiological shunt is increased. |
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