| Autor: |
Khalil, Alaa M, El-Khatib, Ahmed M, Hamouda, Rasha, Elshabrawy, Sonia M, Kandil, Sherif |
| Zdroj: |
Bioinspired, Biomimetic and Nanobiomaterials; 20230101, Issue: Preprints p1-10, 10p |
| Abstrakt: |
One of the major challenges in teeth re-mineralization is the slow rate of mineralization. In this paper, we developed electric field-aided mineralization system for rapidly regenerating teeth-like structure rapidly. The efficacy of application of electric field combined with Nano-chitosan gel, casein phosphopeptide amorphous calcium phosphate gel and their mixture was investigated as re-mineralizing accelerator for artificially demineralized teeth. Teeth samples have been demineralized by using ethylenediaminetetraacetic acid and subsequently subjected to each gel alone and combined with electric field (20 mA- 5 min). The structural analyses of teeth samples were examined by using scanning electron microscope and X-ray diffraction patterns and its hardness was obtained by Vickers micro-hardness test. The results revealed that the addition of chitosan to casein phosphopeptide amorphous calcium phosphate enhanced the re-mineralization of the tooth structure rather than each one individually. Furthermore, the application of electric field has enhanced teeth hardness and showed highest rate of re-mineralization. In conclusion, the proposed technique could be safely used to reduce the consuming time taken in re-mineralization and efficiently it may be used to increase tooth quality. It is suggested to study other biophysical parameters of using electric fields for in vivoapplications. |
| Databáze: |
Supplemental Index |
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