Successful living donor liver transplantation in a patient with hemophilia A and factor VIII inhibitor: A case report with perioperative recommendations

Autor: Kamyszek, Reed W., Sood, Suman L., Sonnenday, Christopher J., Parikh, Neehar D., Westman, Amanda, Englesbe, Michael J., Waits, Seth A., Barrett, Meredith, Fontana, Robert J., Kumar, Sathish S.
Zdroj: American journal of transplantation; June 2023, Vol. 23 Issue: 6 p839-843, 5p
Abstrakt: Liver transplantation in patients with end-stage liver disease and coexisting hemophilia A has been described. Controversy exists over perioperative management of patients with factor VIII inhibitor predisposing patients to hemorrhage. We describe the case of a 58-year-old man with a history of hemophilia A and factor VIII inhibitor, eradicated with rituximab prior to living donor liver transplantation without recurrence of inhibitor. We also provide perioperative management recommendations from our successful multidisciplinary approach.
Databáze: Supplemental Index