| Autor: |
Machlin, L.J., Gabriel, E., Brin, M. |
| Zdroj: |
The Journal of Nutrition; July 1982, Vol. 112 Issue: 7 p1437-1440, 4p |
| Abstrakt: |
The decrease in plasma pyruvate kinase activity after administration of various tocopherols to vitamin E-deficient rats provided the basis for a 3-point parallelslope assay for vitamin E activity. Based on 6 replicate assays, RRR-α-tocopheryl acetate (RRR-α-TA) was 141% as active as all-rac-α-tocopheryl acetate (all-rac-α-TA). This confirms many previous reports with other bioassays and is in agreement with the unit-weight relationships assigned by The National Formulary. 2-ambo-α-Tocopheryl acetate was 97% as active as all-rac-α-TA indicating that only the configuration of the 2-position on the chromanol ring is important in determining the biological activity of α-tocopherol. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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