Effect of Food Intake on Hypermetabolic Response to Burn Injury in Guinea Pigs

Autor: Wolfe, Robert R., Durkot, Michael J., Clarke, Carolyn C., Bode, Hans H., Burke, John F.
Zdroj: The Journal of Nutrition; July 1980, Vol. 110 Issue: 7 p1310-1312, 3p
Abstrakt: We have studied the effect of caloric intake on metabolic rate in normal and burned (20–25% body surface area, BSA) guinea pigs. Food intake was standardized by means of infusing a liquid diet (48 kcal/day) through chronic gastrostomy tubes continuously for 16 hours per day. We found that feeding control animals a diet insufficient to meet their daily caloric requirements nevertheless resulted in a significantly higher basal oxygen consumption (VO2) 8 hours after food than during fasting. The incremental increase in basal VO2induced by feeding burned animals (20–25% BSA) was even greater than in controls. Thus, although basal VO2was similar in control fasted and burned-fasted animals, basal VO2in burned-fed animals was significantly greater than in control-fed animals.
Databáze: Supplemental Index