| Autor: |
Chawla, Rajender K., Hersh, Theodore, Lambe, Dwight W., Wadsworth, Allan D., Rudman, Daniel |
| Zdroj: |
The Journal of Nutrition; December 1976, Vol. 106 Issue: 12 p1737-1746, 10p |
| Abstrakt: |
The purpose of this study was to quantify the growth-promoting effect of a mixture of antibiotics for rats eating diets deficient in protein or an essential amino acid. Male albino weanling rats (70 to 80 g weight, 4 weeks old) were fed (a) a control diet containing all other required nutrients and varying amounts of casein (0 to 27%), or (b) a purified amino acid diet containing all other required nutrients and varying amounts of valine (0 to 70 µmoles/g diet), threonine (0 to 69 µmoles/g diet) or tryptophan (0 to 8.6 µmoles/g diet), with and without an oral antibiotic supplement consisting of neomycin sulfate (10 mg/100 g body weight/day), bacitracin (500 units/100 g body weight/day), and polymyxin B sulfate (1 mg/100 g body weight/day). At suboptimal intake of casein, valine, tryptophan or threonine, rats eating antibiotic-enriched diet showed up to 3 times greater daily body weight gain (ΔBW) than rats eating a similar diet without antibiotics. The growth-promoting effect of antibiotics can be expressed as percent sparing of specified nutrient (casein or individual amino acid), defined as below: |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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