| Autor: |
Mercer, L. Preston, Dodds, Steven J., Smith, Diane L. |
| Zdroj: |
The Journal of Nutrition; November 1987, Vol. 117 Issue: 11 p1936-1944, 9p |
| Abstrakt: |
Parameters derived from the application of the saturation kinetics model (SKM) to rat growth experiments were used to formulate a complete dietary amino acid mix for weanling rats. Dietary ratios and concentrations for indispensable amino acids (IAA) and arginine were calculated using the parameter K0.5. A curve shift technique was used to determine dietary concentrations for conditionally indispensable amino acids (CAA) and dispensable amino acids (DAA). The model was also used to determine a dietary ratio of (IAA + Arg)/(CAA + DAA). Using the dietary amino acid concentrations suggested by the model and an (IAA + Arg)/(CAA + DAA) ratio of 1, a growth response curve was constructed and compared to a similar curve using the amino acid mix of Rogers and Harper. The modeling approach produced a 10–15% improvement in growth over the Rogers and Harper mix. The SKM is discussed in terms of calculating an ideal nutrient ratio and choosing a desired response level. It is demonstrated that the model can rapidly produce accurate estimates for dietary amino acid levels, while minimizing required numbers of laboratory animals. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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