Effects of Dietary Calcium upon Lipid Metabolism in Rats Fed Saturated or Unsaturated Fat

Autor: Yacowitz, H., Fleischman, A.I., Amsden, R.T., Bierenbaum, M.L.
Zdroj: The Journal of Nutrition; July 1967, Vol. 92 Issue: 3 p389-392, 4p
Abstrakt: To study the effects of varying the degree of saturation of dietary fat upon the hypolipemic action of elevated dietary calcium, mature male rats were fed cocoa butter or corn oil with 0.08, 0.2 and 1.2% dietary calcium for 3 weeks. The previously reported hypocholesterolemic and hypotriglyceridemic effects of calcium were observed with both fats. Corn oil significantly elevated serum bile acids. At the 0.08% calcium level, corn oil caused a significantly increased deposition of lipid in the liver and triglycerides in the lung as compared with cocoa butter. Increased dietary calcium tended to reverse this deposition. Although fecal total lipids and bile acids increased significantly with both fats at the 1.2% calcium level, fecal lipid phosphorus and 3-β-hydroxysterol excretion increased only in the presence of cocoa butter. Corn oil caused the excretion of significantly less fecal total lipids than cocoa butter. Calcium was hypolipemic in rats fed either fat; however, the effects of calcium were more pronounced in the presence of saturated fat.
Databáze: Supplemental Index