A Deficiency Disease of Foxes Produced by Feeding Fish

Autor: Green, R.G., Carlson, W.E., Evans, C.A.
Zdroj: The Journal of Nutrition; March 1941, Vol. 21 Issue: 3 p243-256, 14p
Abstrakt: Chastek paralysis is an economically important acute disease of foxes occurring in violent outbreaks on ranches where uncooked fish is included as 10% or more of the ration. It causes a high mortality among nursing pups and intrauterine death of fetuses. The disease may easily be produced experimentally with a diet containing fresh carp, and can be prevented by adding large amounts of thiamine to the same ration. Characteristic neurologic symptoms occur and diagnostic lesions, identical with those of Wernicke’s hemorrhagic polioencephalitis of man, are found in the brain. Pathologic findings, limited therapeutic field trials of thiamine and histories of ranch outbreaks confirm the experimental evidence that Chastek paralysis is fundamentally a B1avitaminosis.
Databáze: Supplemental Index