| Autor: |
Brenner, Sadie, Hessler Brookes, Margaret C., Roberts, Lydia J. |
| Zdroj: |
The Journal of Nutrition; May 1942, Vol. 23 Issue: 5 p459-471, 13p |
| Abstrakt: |
A study of the vitamin A liver stores in relation to the appearance of several alleged subclinical signs was undertaken in rats on a vitamin A-free diet. It was found that:1Whereas 4-week-old rats lost their total vitamin A liver stores after 1 week, hypervitaminotic animals lost 90% of their excess stores after 8 weeks and 98% after 18 weeks. At the thirtieth week of depletion the liver still contained vitamin A.2The vitamin A content of the blood declined rapidly from the hypervitaminotic level, and then decreased more gradually until a plateau was reached for both sexes at about the thirteenth week.3The vitamin A content of the retina decreased to the eighth week of depletion when a plateau was reached.4In the absence of liver stores for several weeks vitamin A was still present in the blood and eye in amounts found in stock rats of weaning age.5A significant sex difference existed. The females stored and retained more vitamin A in the liver than the males, while the males had higher blood levels. |
| Databáze: |
Supplemental Index |
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