Changes in the Activity of Acetyl CoA Carboxylase in the Intestinal Mucosa of the Rat During Development1

Autor: Hynie, Ivo, Hahn, Peter
Zdroj: The Journal of Nutrition; October 1972, Vol. 102 Issue: 10 p1311-1314, 4p
Abstrakt: Acetyl CoA carboxylase (EC 6.4.1.2) activity was determined in the mucosa of the small intestine of rats aged 1 day to 3 months. In the proximal third, activity increased tenfold between days 10 and 24 and about fivefold between day 24 and 3 months. The changes in the 2nd and 3rd were much smaller so that a proximo-distal gradient developed in adult animals. Feeding 16-day-old rats a fat-free diet for 5 days caused an eightfold increase in activity in all three portions of the small intestine. Feeding the same diet to 3-month-old rats doubled the activity in all three portions of the intestine but the already formed proximo-distal gradient remained unchanged.
Databáze: Supplemental Index