| Autor: |
Mulford, Dwight J., Outland, Charlotte E. |
| Zdroj: |
The Journal of Nutrition; March 1957, Vol. 61 Issue: 3 p381-388, 8p |
| Abstrakt: |
A low-choline diet containing 2-amino-2-methyl-1-propanol was fed to male rats, starting at three to 20 weeks of age. When the drug was fed at a level of 10 mg per gram of food, hemorrhages appeared in the kidneys of the three- to 5-week-old animals in 4 to 7 days, and in the 6- to 8-week-old animals in from 8 to 10 days. Kidney lesions occurred in all animals of the three- to 5-week-old group in from 5 to 7 days and in all animals of the 6- to 8-week-old group in from 6 to 9 days. Death occurred in the three- to 5-week animals in from 6 to 9 days. One animal of the 7-week-old group died on the 12th day, while none of the 6- and 8-week groups had died by the 10th and 12th day, respectively. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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