Intentional ABO‐Incompatible Lung Transplantation

Autor: Strüber, M., Warnecke, G., Hafer, C., Goudeva, L., Fegbeutel, C., Fischer, S., Gottlieb, J., Avsar, M., Simon, A.R., Haverich, A.
Zdroj: American journal of transplantation; November 2008, Vol. 8 Issue: 11 p2476-2478, 3p
Abstrakt: We report on a case of intentional blood group incompatible lung transplantation. A blood group O cystic fibrosis patient was mechanically ventilated and put on interventional lung assist for severe respiratory decompensation. Since timely allocation of a blood group O donor lung was impossible, an AB deceased donor lung rescue allocation was accepted and the transplant performed using a pre‐, peri‐ and postoperative antibody depletion protocol including plasmapheresis, ivIg administration, rituximab and immunoadsorption. Nine months after the transplant the patient is at home and well.
Databáze: Supplemental Index