Low Prevalence of Listeria monocytogenesin Human Stool

Autor: Sauders, Brian D., Pettit, David, Currie, Brian, Suits, Paul, Evans, Ann, Stellrecht, Kathleen, Dryja, Diane M., Slate, Donald, Wiedmann, Martin
Zdroj: Journal of Food Protection; January 2005, Vol. 68 Issue: 1 p178-181, 4p
Abstrakt: Listeria monocytogenesis a foodborne pathogen that is found widely in the environment and in a variety of ready-to-eat foods, yet human invasive infection is relatively rare (five cases per million people annually in the United States). Despite wide exposure to this organism, little is known about the prevalence of L. monocytogenesin human stool, and it is not known whether human fecal dispersal contributes to human foodborne transmission. We cultured 827 stool specimens (well formed and loose-watery) from individuals from four large metropolitan areas of New York state for L. monocytogenesand found only 1 (0.12%) positive specimen. L. monocytogeneswas also isolated from the blood of the person with the single positive specimen, and the two isolates were indistinguishable by molecular subtyping (both were ribotype DUP-1042B). This provides further evidence that human L. monocytogenesfecal carriage among persons with and without diarrheal disease is remarkably low. Unlike the case for other foodborne pathogens (e.g., Salmonella), human shedders probably do not contribute significantly to L. monocytogenescontamination of foods. However, we observed a single individual with invasive listeriosis that shed the pathogen in feces, indicating the potential for fecal dispersal of L. monocytogenesfrom persons with listeriosis.
Databáze: Supplemental Index