| Autor: |
Dias, L. C., Oliveira, L. G. de |
| Zdroj: |
Organic Letters; July 2004, Vol. 6 Issue: 15 p2587-2590, 4p |
| Abstrakt: |
Initial efforts toward the total synthesis of the antifungal antibiotics spirofungins A and B are reported. A short and efficient synthesis of the C9−C20 6,6-spiroketal fragments of both compounds is described. This asymmetric approach uses a very efficient alkylation of a lithiated N,N-dimethylhydrazone followed by spiroketal formation under acidic conditions. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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