| Autor: |
Pramanick, Bidhan, Martinez-Chapa, Sergio Omar, Madou, Marc J |
| Zdroj: |
ECS Transactions; April 2016, Vol. 72 Issue: 1 |
| Abstrakt: |
Transdermal drug delivery using microneedles is a minimally invasive procedure which causes little or no pain. We present a novel method for fabricating microneedles using the Carbon-MEMS (C-MEMS) process. The fabrication of an array of hollow microneedles combining UV photolithography and carbonization of a polymer precursor is demonstrated. The shrinkage of the SU-8 microneedles during pyrolysis was analyzed and the pyrolyzed carbon needle structures were characterized using Raman spectroscopy to determine the extent of sp2vs sp3carbon hybridization. Using energy dispersive x-ray spectroscopy we also analyzed the chemical composition of the microneedles. We report here for the very first time the fabrication of glassy carbon hollow microneedles. |
| Databáze: |
Supplemental Index |
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