| Autor: |
Lafeber, Floris P. J. G., Hanssen, R. G. J. M., Bonga, S. E. Wendelaar |
| Zdroj: |
The Journal of Experimental Biology; November 1988, Vol. 140 Issue: 1 p199-208, 10p |
| Abstrakt: |
Hypocalcin isolated from trout corpuscles of Stannius (CS) and bovine parathyroid hormone (bPTH) induce hypocalcaemia when injected intra-arterially in hypercalcaemic, stanniectomized (STX) eels. On a molar basis, both hormones have almost the same potency. Upon injection of hypocalcin we observed a decrease in blood ionic calcium level which fully accounts for the decrease in total calcium. Injections of bPTH also resulted in a decrease of total and ionic calcium concentrations in the blood. The decrease in ionic calcium level upon injection of bPTH, however, did not fully account for the decrease in total calcium concentration of the blood. Nevertheless, hypocalcin and bPTH showed striking similarity in bioactivity in stanniectomized eels. Some similarity in three-dimensional structure of both hormones may underlie this phenomenon. |
| Databáze: |
Supplemental Index |
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