Eco-friendly phytofabrication of silver nanoparticles using aqueous extract of Aristolochia bracteolataLam: its antioxidant potential, antibacterial activities against clinical pathogens and malarial larvicidal effects

Autor: Chinnasamy, Ragavendran, Chinnaperumal, Kamaraj, Cherian, Tijo, Thamilchelvan, Kayalvizhi, Govindasamy, Balasubramani, Vetrivel, Cittrarasu, Perumal, Vivekanandhan, Willie, Peijnenburg, Krutmuang, Patcharin
Zdroj: Biomass Conversion and Biorefinery; November 2024, Vol. 14 Issue: 22 p28051-28066, 16p
Abstrakt: The silver nitrate was reduced into silver nanoparticles by using the Aristolochia bracteolataplant aqueous extract. The green-synthesized nanoparticles were characterized through UV–Vis spectrophotometry, FTIR, EDAX, XRD, and TEM analysis. Results of TEM analysis clearly show that synthesized AgNP size range is 6 to 20 nm. The average particle size and zeta potential value was determined and found to be 16.7 nm and − 24.2 mV, respectively. The silver nanoparticles showed remarkable antibacterial, DPPH, ABTS, and FRAP activity. Silver nanoparticles exhibited strong antiradical effectiveness with minimal concentration. AgNPs had a dose-dependent effect on Anopheles stephensilarvae, with LC50values of 21.3, 45.5, 12.7, and 7.9 and LC90values of 32.4, 65.3, 20.1, and 15.4 µg/mL, respectively. The highest pupal activity was observed at 2.0 µg/mL, with the LC50being 4.0 and the LC90being 9.1 µg/mL, respectively. The biotoxicity assay of A. salinashows 6.33–48.33% mortality, which was exhibited by the A. bracteolata-bioconverted AgNPs. The LC50and LC90values were 610.381 and 6214 µg/mL. No behavioral variations were observed. The present study provides the first scientific information on the antibacterial, larvicidal, and pupicidal properties of AgNPs produced from a leaf extract of A. bracteolata.
Databáze: Supplemental Index