| Autor: |
Magudeeswaran, Vignesh, Velayutham, Jayasudha, Paramasivam, Sriraja Subhasri, Karuppaiah, Gopi, Mariappan, Siva ANANTH, Manickam, Pandiaraj |
| Zdroj: |
ECS Transactions; April 2022, Vol. 107 Issue: 1 |
| Abstrakt: |
Molecularly imprinted polymers (MIPs) having inherent redox activity is developed for reagent-free electrochemical detection of steroid hormone biomarker cortisol. Ferrocenylmethyl methacrylate and acrylic acid were used as redox and functional monomers, respectively. Free radical initiated co-polymerization process was performed in the presence of cortisol as a template to create electroactive MIPs. The copolymerized ferrocenylmethyl methacrylate network provided the redox-active and self-reporting electrochemical platform for detecting redox-inactive biomarkers without using any additional reagents. Cortisol is chosen as the model analyte to evaluate the performance of the self-reporting molecular recognition property. The self-reporting MIPs allowed the quantitative detection of cortisol (as low as 0.5 ng) in the presence of other structurally similar steroid hormones. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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