| Autor: |
Komandur, Kavita, Salma, Ummey, C, Pushpalatha |
| Zdroj: |
ECS Transactions; April 2022, Vol. 107 Issue: 1 |
| Abstrakt: |
A major difficulty for the successful eradication of oral infections is the dilution and rapid elimination of topically applied drugs due to the flushing action of saliva. Hence there is a need for a drug delivery system that can prolong retention of the locally applied drugs in the oral cavity. Aim: To design a liquid bandage containing ginger extracts (GELB) and evaluates its antioxidant efficacy. Methodology: Various concentrations of GELB were formulated and tested for antioxidant activity using DPPH scavenging assay. IC50 value using Graph Prism software version 5.0 by nonlinear regression analysis of % inhibition was recorded for different concentrations of GELB/standard. Results: In the DPPH assay, GELB showed a significant level of dose-dependent DPPH radical scavenging activity with IC50 value of 0.1993% when compared to standard with IC50 value of 4.099 µg/ml. Conclusion: The ginger extract liquid bandage has shown superior antioxidant properties against oral pathogens with satisfactory and sustained drug release. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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