Efzofitimod for the Treatment of Pulmonary Sarcoidosis

Autor: Culver, Daniel A., Aryal, Shambhu, Barney, Joseph, Hsia, Connie C.W., James, W. Ennis, Maier, Lisa A., Marts, Lucian T., Obi, Ogugua Ndili, Sporn, Peter H.S., Sweiss, Nadera J., Shukla, Sanjay, Kinnersley, Nelson, Walker, Gennyne, Baughman, Robert
Zdroj: Chest; 20230101, Issue: Preprints
Abstrakt: Pulmonary sarcoidosis is characterized by the accumulation of immune cells that form granulomas affecting the lungs. Efzofitimod (ATYR1923), a novel immunomodulator, selectively binds neuropilin 2, which is upregulated on immune cells in response to lung inflammation.
Databáze: Supplemental Index