Immunological and virological findings in a patient with exceptional post-treatment control: a case report

Autor: Climent, Núria, Ambrosioni, Juan, González, Tània, Xufré, Cristina, Casadellà, Maria, Noguera-Julian, Marc, Paredes, Roger, Plana, Montserrat, Grau-Expósito, Judith, Mallolas, Josep, Alcamí, José, Sánchez-Palomino, Sonsoles, Miró, José M, Nicolás, David, Xufré, Cristina, Hurtado, Carmen, Rovira, Cristina, Sued, Omar, Brunet, Mercé, López-Diéguez, María, Manzardo, Christian, Agüero, Fernando, Tuset, Montserrat, Guardo, Alberto C, Marcos, Maria A., del Mar Mosquera, María, Muñoz-Fernández, M. Ángeles, Caballero, Miguel, Ligero, Carmen, Fernández, Emma, Marcos, M. Ángeles, Gatell, José M, de Lazzari, Elisa, Gallart, Teresa, Fernandez-Tenreiro, Ana, Gomez, Begoña, Berrocal, Leire, Nicolás, David, Xufré, Cristina, Hurtado, Carmen, Rovira, Cristina, Sued, Omar, Brunet, Mercé, López-Diéguez, María, Manzardo, Christian, Agüero, Fernando, Tuset, Montserrat, Guardo, Alberto C, Marcos, Maria A., Mosquera, María del Mar, Muñoz-Fernández, M. Ángeles, Caballero, Miguel, Ligero, Carmen, Fernández, Emma, Marcos, M. Ángeles, Gatell, José M, de Lazzari, Elisa, Gallart, Teresa, Fernandez-Tenreiro, Ana, Gomez, Begoña, Berrocal, Leire
Zdroj: The Lancet HIV; January 2023, Vol. 10 Issue: 1 pe42-e51, 10p
Abstrakt: Although antiretroviral therapy (ART) is effective in suppressing viral replication, HIV-1 persists in reservoirs and rebounds after ART has been stopped. However, a very few people (eg, elite and post-treatment controllers) are able to maintain viral loads below detection limits without ART, constituting a realistic model for long-term HIV remission. Here, we describe the HIV control mechanisms of an individual who showed exceptional post-treatment control for longer than 15 years.
Databáze: Supplemental Index