| Autor: |
Gubinelli, F., Sarauskyte, L., Venuti, C., Kulacz, I., Cazzolla, G., Negrini, M., Anwer, D., Vecchio, I., Jakobs, F., Manfredsson, F.P., Davidsson, M., Heuer, A. |
| Zdroj: |
Current Research in Neurobiology; 20220101, Issue: Preprints |
| Abstrakt: |
In the last decades different preclinical animal models of Parkinson's disease (PD) have been generated, aiming to mimic the progressive neuronal loss of midbrain dopaminergic (DA) cells as well as motor and non-motor impairment. Among all the available models, AAV-based models of human alpha-synuclein (h-aSYN) overexpression are promising tools for investigation of disease progression and therapeutic interventions. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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