| Autor: |
Takagi, Momoko, Nagai, Suzuna, Kaminaka, Hironori, Akimitsu, Kazuya, Shirasu, Ken, Ichimura, Kazuya |
| Zdroj: |
Plant Signaling & Behavior; December 2022, Vol. 17 Issue: 1 |
| Abstrakt: |
ABSTRACTDisruption of the Arabidopsismitogen-activated protein kinase pathway, MEKK1–MKK1/MKK2–MPK4 (hereafter designated as MEKK1 pathway), leads to the activation of distinct NLRs (nucleotide-binding and leucine-rich repeat receptors), TNL (TIR-type NLR) SMN1, and CNL (CC-type NLR) SUMM2, resulting in dwarf and autoimmune phenotypes. Unlike mekk1and mkk1mkk2mutants, the dwarf and autoimmune phenotypes of mpk4are only partially suppressed by the summ2mutation, suggesting a significant contribution of SMN1to the mpk4phenotypes. However, full suppression of mpk4by the smn1summ2double mutation remains to be elucidated. To address this key question, we generated a mpk4smn1summ2triple mutant and analyzed the dwarf and constitutive cell death phenotypes. The mpk4smn1summ2triple mutant showed restoration of plant size with no detectable cell death, indicating full suppression of the dwarf and autoimmune phenotypes. These results suggest that SMN1 and SUMM2 constitute a robust surveillance system for the MEKK1 pathway against pathogen infection. |
| Databáze: |
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