Autor: |
Leung, Isabel, Templeton, Megan L., Lo, Yun, Rajan, Anusha, Stull, Sylvia M., Garrison, Sarah M., Salter, Alexander I., Smyth, Kimberly S., Correnti, Colin E., Srivastava, Shivani, Yeung, Cecilia C. S., Riddell, Stanley R. |
Zdroj: |
Blood Advances; 20230101, Issue: Preprints |
Abstrakt: |
•Bispecific CAR T cells circumvent outgrowth of antigen-negative tumor cells in vivo.•Tandem and bicistronic CARs have reduced sensitivity to single-antigen tumor cells because of compromised antigen binding and signaling. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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